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Title:Amyotrophic Lateral Sclerosis : New Research
Author:Christine A Murray (ed)
ISBN:1594541795 : 9781594541797
Illustrations:tables & charts
Format:Hardback
Size:180x260mm
Pages:358
Weight: 1.015 Kg.
Published:Nova Science Publishers - May 2006
List Price: 74.99 Pounds Sterling
Availability:In Print
Subjects:Neurology & clinical neurophysiology


ALS, also known as Lou Gehrig’s Disease, is the most common of the motor neuron diseases that cause muscle atrophy. ALS is a chronic, progressively debilitating disease characterised by progressive muscle atrophy starting in the limbs and spreading to the rest of the body, often accompanied by overactive reflexes. It usually manifests itself after the age of 40. The exact cause of ALS is unknown and there is no cure at this time. ALS may be fatal in one year or continue for 10 or more years. This new book includes leading edge research from around the world and covers the aetiology, pathogenesis, symptoms, diagnosis, and treatment of amyotrophic lateral sclerosis (ALS).

Preface; Familial Amyuotrophic Lateral Sclerosis; The Lesson We Can Learn from Familial ALS Patients Carrying a SOD1 Mutation; Interactions Between Excitotoxicity and Oxidative Stress in ALS: Clues for Pharmacotherapy; Mitochondrial Alterations in a Murine Model of Amyotrophic Lateral Sclerosis; Blood Oxidative Stress in Amyotrophic Lateral Sclerosis; Excitability and Potentials of Human Fibres in Amyotrophic Lateral Sclerosis: Model Investigations; Neuroinflammatory Insights into Amyotrophic Lateral Sclerosis; Amyotrophic Lateral Sclerosis: On the Origin of the Degenerated Fibers in the White Matter of the Spinal Cord; Involvement of Neurotrophins and their Common Receptor p75NTR in the Pathology of ALS; The Use of Acoustic Speech Analysis and Dysarthria Profile Tests in Detecting Early Speech Disturbances in Patients with Amyotrophic Lateral Sclerosis; Evaluation of Oesophageal Peristalsis in Amyotrophic Lateral Sclerosis’ Patients with Dysphagia (Early Report); Assessment of Deficient Motor Function of the Hand in Amyotrophic Lateral Sclerosis; Satellite Potentials in Amyotrophic Lateral Sclerosis (ALS) -- a Simulation Study; Magnetic Resonance Spectroscopic Investigation in Amyotrophic Lateral Sclerosis (ALS); Molecular Genetic and Biochemical Studies of Russian Patients with Sporadic Motor Neuron Disease; Index.