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Title:Cell Apoptotic Signalling Path
Author:Charles O Pickens (ed)
ISBN:1600215076 : 9781600215070
Format:Hardback
Size:180x260mm
Pages:222
Weight: .728 Kg.
Published:Nova Science Publishers - September 2007
List Price: 85.99 Pounds Sterling
Availability:In Print
Subjects:Cellular physiology


Apoptosis is the regulated form of cell death. It is a complex process defined by a set of characteristic morphological and biochemical features that involves the active participation of affected cells in a self-destruction cascade. This programmed cell death plays a critical role in physiological functions such as cell deletion during embryonic development, balancing cell number in continuously renewing tissues and immune system development. Additionally, a dysregulation of apoptosis is underlying in numerous pathological situations such as Parkinson, Alzheimer's disease and cancer. A number of studies have pointed out an association between consumption of fruits and vegetables, and certain beverages such as tea and wine, which are rich in polyphenols, with reduced risk of chronic diseases, including cancer. Apoptosis is also the regulatory mechanism involved in the removal of unnecessary cells during development and in tissue homeostasis in a wide range of organisms from insects to mammals. This book focuses on cell apoptotic signalling pathways.

Molecular Biology of Sepsis: Identification and Characterisation of Kep Apoptotic Signalling Pathways; The Implications of Mitochondrial Permeability in the Execution Phase of Apoptosis; Role for NA/H Exchanger 1 (NHE1) in the Control of Apoptotic Pathways; Signalling of Apoptotic Cells towards Alternative Macrophage Activation; Cell Death Mechanisms in Pancreatitis; Osteoclast Apoptosis; Molecular Characterisation and Evolution of Lipopolysaccharide-Induced Apoptotic Pathways in Sponges (Demospongiae, Porifera); Index.