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Title:Cell Apoptosis : Regulation & Environmental Factors
Author:Lawrence B Shultz (ed)
ISBN:1600215084 : 9781600215087
Illustrations:tables & charts
Format:Hardback
Size:180x260mm
Pages:211
Weight: .7 Kg.
Published:Nova Science Publishers - March 2007
List Price: 85.99 Pounds Sterling
Availability:In Print
Subjects:Medical research: Cellular physiology: Cellular biology


Apoptosis is the regulated form of cell death. It is a complex process defined by a set of characteristic morphological and biochemical features that involves the active participation of affected cells in a self-destruction cascade. This programmed cell death plays a critical role in physiological functions such as cell deletion during embryonic development, balancing cell number in continuously renewing tissues and immune system development. Additionally, a dysregulation of apoptosis is underlying in numerous pathological situations such as Parkinson, Alzheimer´s disease and cancer. A number of studies have pointed out an association between consumption of fruits and vegetables, and certain beverages such as tea and wine, which are rich in polyphenols, with reduced risk of chronic diseases, including cancer. Apoptosis is also the regulatory mechanism involved in the removal of unnecessary cells during development and in tissue homeostasis in a wide range of organisms from insects to mammals. This book deals with cell apoptosis regulation and environmental factors.

Preface; Bcl-2 and Mitochondrial Control of Apoptosis as a Mechanism for Regulating Neural Plasticity; Molecular Mechanisms and New Developments in the Regulation of Programmed Cell Death; Prevention of Apoptosis by Down-Regulation of Apoptosis Related Gene Expression Obtained by Nipradilol via Nitric Oxide Donative Action; Kinase Networks in the Regulation of Radiation-Induced Apoptosis Understanding Cascades from Initiation to Promotion of Apoptosis; Recognition and Engulfment of the Apoptotic Cells: Influence of the Environment; Chapter VI.-Vasoactive Intestinal Peptide as Modulator of Cigarette Smoke Extract-Induced Oxidative Stress and Apoptotic Cell Death in Rat Alveolar L2 Cells; Apoptosis Induced by Environmental Factors; Dysregulated Apoptosis in Liver Diseases; The Effect of Catechins on HL-60 Cell Apoptosis; Index.