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Title:Cell Apoptosis Research Advances
Author:Carter R Kettleworth (ed)
ISBN:1600215092 : 9781600215094
Illustrations:b/w illus
Format:Hardback
Size:180x260mm
Pages:358
Weight: 1.012 Kg.
Published:Nova Science Publishers - September 2007
List Price: 85.99 Pounds Sterling
Availability:In Print
Subjects:Medical research: Cellular physiology


Apoptosis is the regulated form of cell death. It is a complex process defined by a set of characteristic morphological and biochemical features that involves the active participation of affected cells in a self-destruction cascade. This programmed cell death plays a critical role in physiological functions such as cell deletion during embryonic development, balancing cell number in continuously renewing tissues and immune system development. Additionally, a dysregulation of apoptosis is underlying in numerous pathological situations such as Parkinson, Alzheimer's disease and cancer. A number of studies have pointed out an association between consumption of fruits and vegetables, and certain beverages such as tea and wine, which are rich in polyphenols, with reduced risk of chronic diseases, including cancer. Apoptosis is also the regulatory mechanism involved in the removal of unnecessary cells during development and in tissue homeostasis in a wide range of organisms from insects to mammals. This book presents important research from around the world.

Cell Death Types at a Glance; Cycling to Death: Involvement of Cell Cycle Molecules in Neuronal Apoptosis; Apoptosis in Human Hematopoietic Stem and Progenitor Cells; Cytochemical and Apoptotic Markers of Tissue Remodelling; Recent Progress in the Studies of Molecular Mechanisms of Apoptosis in Mamalian Preimplantation Embryo; The Role of Cell Death-Specific Modifications in Breaking Tolerance to Self-Antigens; Calcium-Sensing Receptor Mediates Protection from Apoptotic Cell Death; Lysosomal Cysteine Proteinases and their Inhibitors in Neurodegenerative Diseases; Activation of C-Jun NH2-Terminal Kinase during Pancreas Preservation, Islet Isolation, and Islet Transplantation; The Role of Caspases in Cardiovascular Diseases; TNF signalling cascades. Cell death and survival; Impact and Significance of Apoptosis in Human Ejaculated Spermatozoa; Index.