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| Title: | Chronic Lymphocytic Leukemia Research Focus
|
| Author: | Chadi Nabhan (ed) |
| ISBN: | 1600215262 : 9781600215261 |
| Illustrations: | tables & charts |
| Format: | Hardback |
| Size: | 180x260mm |
| Pages: | 226 |
| Weight: | .688 Kg. |
| Published: | Nova Science Publishers - September 2007 |
| List Price: | 85.99 Pounds Sterling |
| Availability: | In Print |
| Subjects: | Medical research: Oncology |
Chronic lymphocytic leukaemia (or "chronic lymphoid leukaemia"), known for short as CLL, is a type of leukaemia in which too many lymphocytes are produced. Although the malignant lymphocytes in CLL may look normal and mature, they are not and these cells may not cope effectively with infection. CLL is the most common form of leukaemia in adults. Men are twice as likely to develop CLL as women. However, the key risk factor is age. Over 75% of new cases are diagnosed in patients over age 50. This book presents important research from around the world in this field.
Risk Stratification in the Management of Chronic Lymphocytic Leukaemia (CLL); New Research in Chronic Lymphocytic Leukaemia; Transplantation Strategies for the Treatment of Chronic Lymphocytic Leukaemia; What is the Clinical and Biological Significance of the BCL-2 Family n Apoptosis Regulation in B-Cell Chronic Lymphocytic Leukaemia (CLL)?; Mode of Action of Rituximab in Chronic Lymphocytic Leukaemia; Activation of Tis11b, an Inducer of MRNA Instability and Induction of Apoptosis; Genetic Factors Impacting the Biology of B Cell Chronic Lymphocytic Leukaemia (B-CLL); The "In Vitro Apoptosis" Profile in CLL Correlates with some Prognostic Markers, Treatment History and In Vivo Response to Treatment; CD38 Expression in B-Cell Chronic Lymphocytic Leukaemia: What have we learned?; Novel and Uncommon Chromosome Aberrations in Chronic-Lymphocytic Leukaemia: Cytogenetic, FISH and Clinical Evaluation; Index.
