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| Title: | Dopamine Research Advances
|
| Author: | Akiyama Watanabe (ed) |
| ISBN: | 1600218202 : 9781600218200 |
| Illustrations: | tables & charts |
| Format: | Hardback |
| Size: | 180x260mm |
| Pages: | 225 |
| Weight: | .66 Kg. |
| Published: | Nova Science Publishers - June 2007 |
| List Price: | 85.99 Pounds Sterling |
| Availability: | In Print |
| Subjects: | Biochemistry |
Dopamine is a phenethylamine naturally produced by the human body. In the brain, dopamine functions as a neurotransmitter, activating the five types of dopamine receptor -- D1, D2, D3, D4 and D5, and their variants. Dopamine is produced in several areas of the brain, including the substantia nigra. Dopamine is also a neurohormone released by the hypothalamus. Its main function as a hormone is to inhibit the release of prolactin from the anterior lobe of the pituitary. Dopamine can be supplied as a medication that acts on the sympathetic nervous system, producing effects such as increased heart rate and blood pressure. However, since dopamine cannot cross the blood-brain barrier, dopamine given as a drug does not directly affect the central nervous system. To increase the amount of dopamine in the brains of patients with diseases such as Parkinson's disease and Dopa-Responsive Dystonia, L-DOPA (levodopa), which is the precursor of dopamine, can be given because it can cross the blood-brain barrier. This book presents new research in the field.
Preface; Dopamine Control of Sleep and Arousal; A Circuit Dynamics Theory of Complex Dopaminergic Modulation of Prefrontal Cortical Activity and its Relevance to Schizophrenia; The Life Cycle of the Dopaminergic Neurons in the Substantia Nigra; Electrophysiological and Neurochemical In Vivo Studies on Serotonin 5-HT 2C Control of Central Dopaminergic Function; Dopamine Effects on the Adrenal Gland of the Newt Triturus Carnifex (Amphibia, Urodela); Serotonin 5-HT 2C Receptor and Dopamine Function in Depression; A Possible Role for Intracellular Pathways Activation in the Modulation of Learning and Memory Processes by the Dopaminergic and Opioid Systems Interaction; Dopamine System and its Modulation by Nitric Oxide: Approaches in Experimental Parkinson and Schizophrenia; Dopamine Receptors Regulation by Non-Dopaminergic Mechanisms; Index.
