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| Title: | Cancer Metastases Research
|
| Author: | Akira Watanabe (ed) |
| ISBN: | 1604561300 : 9781604561302 |
| Illustrations: | tables & charts |
| Format: | Hardback |
| Size: | 180x260mm |
| Pages: | 301 |
| Weight: | .89 Kg. |
| Published: | Nova Science Publishers - March 2008 |
| List Price: | 85.99 Pounds Sterling |
| Availability: | In Print |
| Subjects: | Health systems & services |
Metastasis is the spread of a disease from one organ or part to another non-contiguous organ or part. Only malignant tumour cells and infections have the capacity to metastasise. Cancer cells can "break away" from a primary tumour, penetrate into lymphatic and blood vessels, circulate through the bloodstream, and grow in a distant focus (metastasise) in normal tissues elsewhere in the body. Metastasis is considered a hallmark of malignancy. All tumours can metastasise albeit to varying degrees, barring a few exceptions (eg. Glioma and Basal cell carcinoma never metastasize). When cancer cells spread to form a new tumour, it is called a secondary, or metastatic tumour, and its cells are like those in the original tumour. This means, for example, that if breast cancer spreads (metastasizes) to the lung, the secondary tumour is made up of abnormal breast cells (not abnormal lung cells). The disease in the lung is then called metastatic breast cancer (not lung cancer). Only malignant tumour cells and infections have the capacity to metastasize. This book presents the latest research in the field from around the world.
Preface; Disseminated Tumor Cells: Detection, Markers and Prognostic/predictive Significance; Recent Advances in Nuclear Medicine: Radiopharmaceutical Chemistry of Agents Used for Lymphoscintigraphy and the Sentinel Node Biopsy; The S100 Family Proteins in Tumour Progression; Association of p53, Ki-67, COX-2, and Her-2 Expressions, as well as T-Stage and Histopathologic Grade, with Occurrence of Metastases and Survival in Renal Cell Carcinoma; Correlation between Metabolic Enzymes of Nucleic Acid in Colorectal Cancer Patients and FRNA/TSIR, Prognostic Factors; Demonstration and Partial Identification of Aberrant MUC1 Bearing Tn Antigen in Rat Ascites Hepatoma AH109A Cells with Strong Lymph Node Metastasis Propensity; Modern Methods for Molecular Risk Profiling in Gastrointestinal Cancer; Extranodal Spread as a Marker for Poor Prognosis and the Need for Postoperatieve Chemoradiation: Some Critical Thoughts; Tumour Biology of Colorectal Liver Metastases; Colorectal Cancer Liver Metastases: Destruction or Resection?; Lung metastases: epidemiology, clinical presentation and imaging; Biology of Esophageal Cancer: Mechanisms of Resistance and Metastases; Bisphosphonate Therapy for Patients with Osteolytic and Osteoblastic Bone Metastases from Breast or Prostate Cancer; Index.
