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| Title: | Motor Neuron Disease Research Progress
|
| Author: | Raffaele L Mancini (ed) |
| ISBN: | 1604561556 : 9781604561555 |
| Illustrations: | tables & charts |
| Format: | Hardback |
| Size: | 180x260mm |
| Pages: | 310 |
| Weight: | .834 Kg. |
| Published: | Nova Science Publishers - May 2008 |
| List Price: | 85.99 Pounds Sterling |
| Availability: | In Print |
| Subjects: | MEDICINE |
The motor neuron diseases (or motor neuron diseases) (MND) are a group of progressive neurological disorders that destroy motor neurons, the cells that control voluntary muscle activity such as speaking, walking, breathing, and swallowing. Neurological examination presents specific signs associated with upper and lower motor neuron degeneration. Signs of upper motor neuron damage include spasticity, brisk reflexes and the Babinski sign. Signs of lower motor neuron damage include weakness and muscle atrophy. Every muscle group in the body requires both upper and lower motor neurons to function. It is a common misconception that "upper" motor neurons control the arms, while "lower" motor neurons control the legs. The signs described above can occur in any muscle group, including the arms, legs, torso, and bulbar region. Symptoms usually present between the ages of 50-70, and include progressive weakness, muscle wasting, and muscle fasciculations; spasticity or stiffness in the arms and legs; and overactive tendon reflexes. Patients may present with symptoms as diverse as a dragging foot, unilateral muscle wasting in the hands, or slurred speech. This new book presents the latest research from around the globe.
Preface; Current Concepts and Research in Multidisciplinary Management of Amyotrophic Lateral Sclerosis. ; Coupling ER stress to motor neuron degeneration in ALS; Transcranial Magnetic Stimulation in Amyotrophic Lateral Sclerosis: Diagnostic Value and Therapeutic Perspectives; Mining genomic and proteomic data for biomarkers of amyotrophic lateral sclerosis and related motor neuron disease; Amyotrophic Lateral Sclerosis: what goals for cell therapy? ; T cells may be credible therapeutic targets in amyotrophic lateral sclerosis; Mitochondrial involvement in amyotrophic lateral sclerosis; Activity-dependent conduction block detected by magnetic stimulation of the cervical root in multifocal motor neuropathy: magnetic fatigue test; Oxidative DNA damage, DNA repair and Amyotrophic Lateral Sclerosis. ; Post-Polio Syndrome: Recent Progress and Future Directions; Targeting the Inhibition of Cyclin-Dependent Kinases as a Potential Strategy for Treating Amyotrophic Lateral Sclerosis. ; Recent Advances in Respiratory Care for Motor Neuron Disease; Transcranial Magnetic Stimulation in Amyotrophic Lateral Scerlosis: A Review of Recent Developments; Index.
