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Title:Cancer & Stem Cells
Author:Thomas Dittmar & Kurt S Zänker (eds)
ISBN:1604564784 : 9781604564785
Illustrations:colour & b/w illus
Format:Hardback
Size:180x260mm
Pages:220
Weight: .69 Kg.
Published:Nova Science Publishers - October 2008
List Price: 74.5 Pounds Sterling
Availability:In Print
Subjects:Oncology


Today, cancer is the second most prevalent cause of death, after heart disease, in the industrialised world. Till now, and despite promising results in cancer research, the primary cause of death in cancer is still 1: the formation of metastases at distant organs sites, 2: the presence of cancer cells that are resistant to current cancer therapies (chemotherapy/radiation) and which cause cancer relapse. Within the past three years it became evident that also solid tumour tissues contain a kind of stem cells, so called cancer cells. These cancer stem cells have been described as chemo-radiation therapy resistant tumour initiating cells. The purpose of this book is to summarise the latest findings about the role of stem cells in cancer.

Preface; Cancer Stem Cells: A Definition; Mathematical Modeling of Stem Cells Related to Cancer; Where Do Cancer Stem Cells Come From?; Mismatch Repair Deficiencies and Origin of Cancer Stem Cells; Cancer Stem Cells in Hematological Malignancies; Stem Cells in Solid Tumors; Cancer Stem Cells and Metastasis; Exercise, Stem Cells and Cancer; Human Adult Stem Cells as Targets for Cancer Stem Cells: Evolution: Oct-4 Gene and Cell to Cell Communication; Index.