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| Title: | Medicinal Chemistry Research Progress
|
| Author: | Giulia P Colombo & Sofia Ricci |
| ISBN: | 1604565802 : 9781604565805 |
| Format: | Hardback |
| Published: | Nova Science Publishers - September 2008 |
| List Price: | 85.99 Pounds Sterling |
| Availability: | Not yet published |
| Subjects: | Pharmacology |
Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacology involved with designing, synthesising and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and development of new chemical entities suitable for therapeutic use. It also includes the study of existing drugs, their biological properties, and their quantitative structure-activity relationships (QSAR). Pharmaceutical chemistry is focused on quality aspects of medicines and aims to assure fitness for the purpose of medicinal products. Medicinal chemistry is a highly interdisciplinary science combining organic chemistry with biochemistry, computational chemistry, pharmacology, pharmacognosy, molecular biology, statistics, and physical chemistry. This book presents leading research from around the world in this frontal field.
Preface; An Open Letter to the Community of Organic Chemists; Alzheimer's Disease, the Importance of Aß and the Hopes for Chemo Preventatives ; Novel Class of Antibacterial Agents: Inhibitors of Enoyl-acyl Carrier Protein Reductases FabI and FabK; Progress in the Discovery of SERCA Inhibitors; G-Quadruplex Interactive Telomerase Inhibitors: An Exciting Field to be Explored, with Some Open Challenges on the Biological Evaluation; Polyenthylenimine in Medicinal Chemistry; Multifunctional Delivery Vehicles for Biomedical Applications: Polyenthylenimine as a Multipurpose Polymer; Putative Bioactive Conformers of Small Molecules: A Concerted Approach Using NMR Spectroscopy and Computational Chemistry; The N-terminal Part of the Ligand-Binding Domain of the Human Estrogen Receptor Alpha: A New Target for Estrogen Disruptors; Anticancer Targets with Peptidomimetics as Ligands; Index.
