Gazelle Book Services Limited.
White Cross Mills, Hightown, LANCASTER LA1 4XS, United Kingdom.
Telephone: +44(0)1524 68765
Fax: +44(0)1524 63232
Email: sales@gazellebooks.co.uk
Web: www.gazellebooks.co.uk
| Title: | Coronary Circulation in Nonsmokers & Smokers
|
| Author: | Aurelio Leone |
| ISBN: | 1604566086 : 9781604566086 |
| Illustrations: | tables & charts |
| Format: | Hardback |
| Size: | 180x260mm |
| Pages: | 247 |
| Weight: | .768 Kg. |
| Published: | Nova Science Publishers - October 2008 |
| List Price: | 74.5 Pounds Sterling |
| Availability: | In Print |
| Subjects: | Cardiovascular medicine |
There is a strong relationship between cigarette smoking and the risk of cardiovascular events. Smoking influences negatively coagulation -- fibrinolysis cascade at any level, although it acts primarily on those pathways that are most important for an effective clot formation: endothelium, platelets, and fibronogen. Moreover, coronary circulation is the target organ of the damage due to smoking esposure. Endothelial dysfunction is a main consequence of smoke compounds with significant changes in initiating physiologic coagulation process; platelet adhesiveness and aggregation increases as a result of smoking; finally, fibrinogen/fibrin framework strengthens clot thickness. Therefore, the whole coagulation cascade activates the thrombi formation pathway under smoking action. The risk of thrombotic cardiovascular events increases its frequency with more severe atherosclerotic alterations if compared to similar events in non-smokers. Therefore, the knowledge of the characteristic alterations of the coronary circulation typically due to smoking and its comparison with those observed in similar people who are not smoking is basic to better understand the problems related to the subject.
Preface; Anatomy of the Coronary Arteries; Physiology of Coronary Circulation; Humoral and Metabolic Regulation of Coronary Circulation; Coronary Vascular Endothelium; Biochemistry of smoking compounds; Types of Coronary Vessel and Heart Damage; Coronary Atherosclerosis; Coronary Circulation in Nonsmokers; Coronary Circulation in Smokers; Comparison of Coronary Lesions in Nonsmokers and Smokers; Ischemic Heart Disease; Coronary Surgery and Smoking; Final Remarks; Index.
